2003年8月太阳集团tyc33455工程力学系博士后出站留校至今。主讲研究生课程《膜片钳技术与细胞电生理》和本科生课程《细胞与分子力学》。

北京市生物力学专业委员会委员，Scientific Reports编委，Frontiers in Neuroscience客座编辑

细胞生物力学、细胞电生理

近年来主要采用力学手段和电生理方法研究与心血管疾病和神经系统疾病相关的科学与临床问题。作为课题负责人, 多次承担国家自然科学基金、校内基础研究基金和太阳集团tyc33455自主科研计划、企业合作项目等课题，参与了国家重大研发计划研究等多项课题研究。

Sun YL, Zhao HC*. Mechanical stimulation induces electrical coupling via TNTs through calcium-dependent mechanisms in C2C12 cells. Biochemical and Biophysical Research Communications, 2025, 152186.

Sun YL, Zhang HK, Zavodnik IB, Zhao HC*, Feng XQ*. Mechanical properties of intercellular tunneling nanotubes formed by different mechanisms. Heliyon, 2024, 10: e36265.

Liu SS, Wu XA , Yu Y, Wen XW, Yu Z Feng XQ, Zhao HC*. Geometric confinement guides the expression of cancer stem cell molecular markers CD44 via cell traction forces. ACS Biomaterials Science & Engineerring, 2020, 6: 4623-4630.

Yu Y, Liu SS, Wu XA, Yu Z, Xu YS, Zhao WJ, Zayodnik I, Zheng JP, Li C, Zhao HC*. Mechanism of stiff substrates up-regulate cultured neuronal network activity. ACS Biomaterials Science & Engineerring , 2019, 5: 3475-3482.

Wen YQ, Gao XH, Wang AP, Yang Y, Liu SS, Yu Z, Song GB, Zhao HC*. Substrate stiffness affects neural network activity in an extracellular matrix proteins dependent manner. Colloids and Surfaces B-Biointerfaces, 2018, 170, 7290735.

Zhang ZG, Wen YQ, Du J, Yu Y, Liu SS, Wu XA, Zhao HC*. Effects of mechanical stretch on the functions of BK and L-type Ca²⁺ channels in vascular smooth muscle cells. Journal of Biomechanics, 2018, 67: 18-23.

Zhao HC, Yu Y, Wu XA, Liu SS , Liu BL , Jiang LH, Feng XQ. A Role of BK channel in regulation of Ca²⁺ channel in ventricular myocytes by substrate stiffness. Biophysical Journal, 2017, 112: 1406-1416.

Zhang QY, Yu Y, Zhao HC*. The effect of matrix stiffness on biomechanical properties of chondrocytes. Acta Biochimica et Biophysica Sinica, 2016, 48: 958-965.

Zhang QY, Zhang YY, Xie J, Liu BL, Wu XA, Huo B, Jiang LH*, Zhao HC*. Stiff substrates enhance cultured neuronal network activity. Scientific Reports, 2014, 4: 6215.

Xie J, Zhang QY, Zhu T, Zhang YY, Liu BL, Xu JW, Zhao HC*. Substrate stiffness-regulated matrix metalloproteinase output in myocardial cells and cardiac fibroblasts: Implications for myocardial fibrosis. Acta Biomaterialia, 2014, 10：2463-2472.

Xie J, Zhang YY, Xu JW, Kolesnikov SS, Sung KLP, Zhao HC. TGF-beta1 induces the different expressions of lysyl oxidases and matrix metalloproteinases in anterior cruciate ligament and medial collateral ligament fibroblasts after mechanical injury. Journal of Biomechanics, 2013, 46；890-898.

Zhao HC*, Sokabe M. Tuning the mechanosensitivity of a BK channel by changing the linker length. Cell Research, 2008: 18: 871-878.